BDBM50208591 CHEMBL3885292

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C#N)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1C

InChI Key InChIKey=BSPOXGNPEWSHFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208591   

TargetTyrosine-protein kinase JAK3(Human)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208591(CHEMBL3885292)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human JAK3 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208591(CHEMBL3885292)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human JAK2 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208591(CHEMBL3885292)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed