BDBM50208820 (3,4-dihydro-1H-isoquinolin-2-yl)-(2,3,4-trihydroxy-5-isopropylphenyl)methanone::(3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy-5-isopropylphenyl)methanone::CHEMBL220055

SMILES CC(C)c1cc(C(=O)N2CCc3ccccc3C2)c(O)c(O)c1O

InChI Key InChIKey=BHMAXGYZHGTXAG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208820   

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208820((3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208820((3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy...)
Affinity DataIC50: 3.82E+4nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Bcl2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208820((3,4-dihydroisoquinolin-2(1H)-yl)(2,3,4-trihydroxy...)
Affinity DataIC50: 3.82E+4nMAssay Description:Inhibition of human Bcl-2 protein by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed