BDBM50208821 2-(2,3,4-trihydroxy-5-isopropylbenzoyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonicacid phenethylamide::CHEMBL219775

SMILES CC(C)c1cc(C(=O)N2CCc3ccc(cc3C2)S(=O)(=O)NCCc2ccccc2)c(O)c(O)c1O

InChI Key InChIKey=QDGGZDBYCDBSGQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208821   

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208821(2-(2,3,4-trihydroxy-5-isopropylbenzoyl)-1,2,3,4-te...)
Affinity DataKi:  590nMAssay Description:Displacement of FAM-Bid BH3 peptide from human recombinant Bcl2 by FP-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50208821(2-(2,3,4-trihydroxy-5-isopropylbenzoyl)-1,2,3,4-te...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Bcl2 by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed