BDBM50209168 (R)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile::CHEMBL234706
SMILES CN(C)[C@@H]1CCC(=CC1)c1c[nH]c2ccc(cc12)C#N
InChI Key InChIKey=RSNYUBDIPFPZKJ-AWEZNQCLSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50209168
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Displacement of [125I]Nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Displacement of [I125]nisoxetine from human NET transfected in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Displacement of [125I]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Displacement of [I125]RTI-55 from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Displacement of [I125]RTI-55 from human DAT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair