BDBM50209172 (S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole-5-carbonitrile::CHEMBL234705

SMILES CN(C)[C@H]1CCC(=CC1)c1c[nH]c2ccc(cc12)C#N

InChI Key InChIKey=RSNYUBDIPFPZKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209172   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209172((S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole...)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209172((S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209172((S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole...)
Affinity DataIC50: 37nMAssay Description:Displacement of [125I]Nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209172((S)-3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indole...)
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed