BDBM50209513 CHEMBL245788::{[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-yl]-methyl-amino}-acetic acid

SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2ccc(F)cc2c(N(C)CC(O)=O)c1C#N

InChI Key InChIKey=VMVYQMLYTWPIEP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209513   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bayer Pharmaceuticals

Curated by ChEMBL

LigandBDBM50209513({[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-qui...)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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