BDBM50209521 3-[2-(2'-trifluoromethyl-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid::CHEMBL439043

SMILES OC(=O)CCNc1cc(nc2ccccc12)-c1ccc(cc1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=YSPVSIDYPNVZFB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209521   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bayer Pharmaceuticals

Curated by ChEMBL

LigandBDBM50209521(3-[2-(2'-trifluoromethyl-biphenyl-4-yl)-quinolin-4...)Copy SMILESCopy InChI

Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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