BDBM50209583 CHEMBL427438::[Ncy(methyl)10]acyline

SMILES CS[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCNC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](Cc1ccc(NC(C)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O

InChI Key InChIKey=MNOHGPTZCIGJAF-SLOMUXTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209583   

TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583(CHEMBL427438 | [Ncy(methyl)10]acyline)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583(CHEMBL427438 | [Ncy(methyl)10]acyline)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed