BDBM50209785 CHEMBL3884327

SMILES Oc1ccc(\C=C\C(=O)NCc2cn(C[C@@H]3Cc4c(CN3)[nH]c3ccccc43)nn2)cc1O

InChI Key InChIKey=COAMHZJQGVWEHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209785   

TargetBeta-secretase 1(Human)
Chiang Mai University

Curated by ChEMBL
LigandPNGBDBM50209785(CHEMBL3884327)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using beta-secretase substrate 4 after 30 mins by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Chiang Mai University

Curated by ChEMBL
LigandPNGBDBM50209785(CHEMBL3884327)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed