BDBM50209796 CHEMBL3885011

SMILES COC(=O)Cc1c(C)n(Cc2ccc(cc2)-c2cn(CCCCCCCC(=O)NO)nn2)c2ccc(OC)cc12

InChI Key InChIKey=ADORMHQFWRYXJP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50209796   

TargetHistone deacetylase 6(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin) after 20 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 181nMAssay Description:Inhibition of HDAC3 (unknown origin) after 5 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 209nMAssay Description:Inhibition of HDAC2 (unknown origin) after 24 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 251nMAssay Description:Inhibition of HDAC1 (unknown origin) after 24 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 394nMAssay Description:Inhibition of HDAC8 (unknown origin) after 2.5 hrs by SAMDI mass spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition for 2 mins by Cayman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50209796(CHEMBL3885011)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of sheep COX1 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition for 2 mins by Cayman based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2018
Entry Details Article
PubMed