BDBM50210721 CHEMBL397714::N1-((2S,3R)-4-(3-ethylbenzylamino)-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl)-N3,N3-dipropylbenzene-1,3,5-tricarboxamide

SMILES CCCN(CCC)C(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNCc1cccc(CC)c1)C(N)=O

InChI Key InChIKey=STJWSMTYMITMCI-IOWSJCHKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210721   

TargetCathepsin D(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210721(CHEMBL397714 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210721(CHEMBL397714 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed