BDBM50211013 CHEMBL396318::methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylate

SMILES COC(=O)C1=C(CCCCC1)c1cccc(Cl)c1

InChI Key InChIKey=JINIYXOBIKXUET-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211013   

TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211013(methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylat...)
Affinity DataKi:  3.78E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211013(methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylat...)
Affinity DataKi:  2.20E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211013(methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylat...)
Affinity DataKi:  8.50E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211013(methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylat...)
Affinity DataKi:  4.63E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed