BDBM50211428 CHEMBL245936::N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-ylamino)piperidine-1-carboxamide

SMILES CCNC(=O)N1CCC(CC1)Nc1nccc(n1)-c1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=ZYWJPJYYTUCZHN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50211428   

TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 22nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of cJun translocation in IL-1-beta-stimulated A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211428(N-ethyl-4-(4-(2-phenyl-1H-indol-3-yl)pyrimidin-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 by IMAP technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed