BDBM50211600 CHEMBL3907577

SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=WFALAHLDCCYRAJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211600   

TargetCarbonic anhydrase 2(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211600(CHEMBL3907577)
Affinity DataKi:  0.800nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211600(CHEMBL3907577)
Affinity DataKi:  9.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211600(CHEMBL3907577)
Affinity DataKi:  312nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211600(CHEMBL3907577)
Affinity DataKi:  4.76E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed