BDBM50211980 1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyrazole-5-carboxamide::CHEMBL391069

SMILES O=C(Nc1cnc2ccccc2c1)c1ccnn1CCc1ccncc1

InChI Key InChIKey=UXBBSNXOJUJAHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211980   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211980(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)
Affinity DataIC50: 180nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211980(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)
Affinity DataIC50: 380nMAssay Description:Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211980(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed