BDBM50212031 2-(4-(3-morpholino-3-oxopropyl)phenylamino)-4-phenylpyrimidine-5-carbonitrile::CHEMBL233456

SMILES O=C(CCc1ccc(Nc2ncc(C#N)c(n2)-c2ccccc2)cc1)N1CCOCC1

InChI Key InChIKey=VHVYVRJZMOJNQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212031   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212031(2-(4-(3-morpholino-3-oxopropyl)phenylamino)-4-phen...)
Affinity DataIC50: 180nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50212031(2-(4-(3-morpholino-3-oxopropyl)phenylamino)-4-phen...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed