BDBM50212244 CHEMBL3891027

SMILES CCCCCC[C@@H](CCCCCC(=O)Nc1ccccc1)C(=O)NO

InChI Key InChIKey=DIBNKUUJXGHEOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212244   

TargetHistone deacetylase 8(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50: 5.30E+5nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212244(CHEMBL3891027)
Affinity DataIC50: 5.80E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed