BDBM50212245 CHEMBL435160

SMILES ONC(=O)C(CCCCCC(=O)Nc1ccccc1)Cc1ccccc1

InChI Key InChIKey=DPPQTBNAWODKHL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50212245   

TargetHistone deacetylase 8(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length human C-terminal His-tag HDAC8 expressed in baculovirus expression system preincubated for 15 mins followed by HDAC-Glo sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC6 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of HDAC1 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of HDAC3 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of HDAC2 in human HeLaS3 cells preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 45 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50212245(CHEMBL435160)
Affinity DataIC50: 2.26E+5nMAssay Description:Inhibition of HDAC by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed