BDBM50212312 6(4-chloro-3-cyclopropylmethoxy-phenyl)-7-isopropyl-2-methyl-3H-quinazolin-4-one::6-(4-chloro-3-(cyclopropylmethoxy)phenyl)-7-isopropyl-2-methylquinazolin-4(3H)-one::CHEMBL436839

SMILES CC(C)c1cc2nc(C)[nH]c(=O)c2cc1-c1ccc(Cl)c(OCC2CC2)c1

InChI Key InChIKey=JERXWDBVRYWKDD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212312   

LigandPNGBDBM50212312(6(4-chloro-3-cyclopropylmethoxy-phenyl)-7-isopropy...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as blockade of acid-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212312(6(4-chloro-3-cyclopropylmethoxy-phenyl)-7-isopropy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of calcium influx evoked by capsaicin in human TRPV1 expressing cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212312(6(4-chloro-3-cyclopropylmethoxy-phenyl)-7-isopropy...)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as blockade of acid-induced receptor activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212312(6(4-chloro-3-cyclopropylmethoxy-phenyl)-7-isopropy...)
Affinity DataIC50: 105nMAssay Description:Inhibition of low pH activation of rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed