BDBM50212490 3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-4,4-dimethyl-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (4-hydroxy-cyclohexyl)-amide::CHEMBL233640

SMILES COc1cc-2c(cc1C(=O)N[C@H]1CC[C@H](O)CC1)C(C)(C)c1c(n[nH]c-21)-c1ccc(cc1)-c1ccc(O)cc1

InChI Key InChIKey=LUUBZSSWAIDDAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212490   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212490(3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-4,4-dimethy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed