BDBM50213311 2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyloxy)benzo[b]thiophen-3-yl)acetic acid::CHEMBL234588

SMILES OC(=O)Cc1csc2cc(OCc3cccc(COc4ccc(cc4)C(F)(F)F)c3)ccc12

InChI Key InChIKey=PSCZHGLGZAJATA-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50213311   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  963nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  5.79E+3nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  5.79E+3nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  964nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  15nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213311(2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed