BDBM50213321 2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)benzo[b]thiophen-3-yl)acetic acid::CHEMBL233978

SMILES OC(=O)Cc1csc2cc(OCc3cc(on3)-c3ccc(Cl)cc3)ccc12

InChI Key InChIKey=ISEMTHSDRXTHAL-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213321   

LigandPNGBDBM50213321(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50213321(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50:  3.82E+3nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50213321(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50213321(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataEC50:  226nMAssay Description:Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed