BDBM50213334 2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)benzofuran-3-yl)acetic acid::CHEMBL391068

SMILES OC(=O)Cc1coc2cc(OCc3cc(on3)-c3ccc(Cl)cc3)ccc12

InChI Key InChIKey=USGOBGVRHPNUJT-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213334   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213334(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataEC50:  323nMAssay Description:Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213334(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50:  81nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213334(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213334(2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...)
Affinity DataIC50:  2.38E+3nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed