BDBM50214023 (1S,3S)-N1-(5-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine::CHEMBL248694

SMILES COc1cccc2nc(N[C@H]3CCC[C@@H](C3)NCc3ccsc3)ccc12

InChI Key InChIKey=QGLGWGGLYILCFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214023   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214023((1S,3S)-N1-(5-methoxyquinolin-2-yl)-N3-(thiophen-3...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTP-gamma-S accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214023((1S,3S)-N1-(5-methoxyquinolin-2-yl)-N3-(thiophen-3...)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed