BDBM50214034 (1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine::CHEMBL250516

SMILES COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc3ccsc3)nc2c1

InChI Key InChIKey=QUSHDRQZFJGEQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214034   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214034((1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(t...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214034((1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(t...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTP-gamma-S accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed