BDBM50214049 (1S,3S)-N1-(6-fluoro-4-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine::CHEMBL399367

SMILES COc1cc(N[C@H]2CCC[C@@H](C2)NCc2ccsc2)nc2ccc(F)cc12

InChI Key InChIKey=RSDJLPYXEAUVTE-IRXDYDNUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214049   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214049((1S,3S)-N1-(6-fluoro-4-methoxyquinolin-2-yl)-N3-(t...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50214049((1S,3S)-N1-(6-fluoro-4-methoxyquinolin-2-yl)-N3-(t...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed