BDBM50214225 CHEMBL398557::N-(5-((S)-3-((S)-1-(3,4-dimethoxyphenyl)-2-phenylethylamino)-2-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide

SMILES COc1ccc(cc1OC)[C@H](Cc1ccccc1)NC[C@@H](O)Cc1ccc(O)c(NS(C)(=O)=O)c1

InChI Key InChIKey=FAPFLIWIGPTUPT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214225   

TargetBeta-3 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214225(N-(5-((S)-3-((S)-1-(3,4-dimethoxyphenyl)-2-phenyle...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]iodocyanopindolol from cloned human adrenergic beta-3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214225(N-(5-((S)-3-((S)-1-(3,4-dimethoxyphenyl)-2-phenyle...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]iodocyanopindolol from human cloned adrenergic beta-2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214225(N-(5-((S)-3-((S)-1-(3,4-dimethoxyphenyl)-2-phenyle...)
Affinity DataKi:  560nMAssay Description:Displacement of [125I]iodocyanopindolol from human cloned adrenergic beta-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed