BDBM50215010 CHEMBL251144::N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino)propan-2-yl)benzamide

SMILES Nc1ccccc1NC(=O)c1ccc(cc1)C(C(=O)Nc1ccccc1)C(=O)Nc1ccccc1

InChI Key InChIKey=PQBSIJBZIHNQIM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50215010   

TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 313nMAssay Description:Inhibition of human HDAC2 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 697nMAssay Description:Inhibition of human HDAC3 expressed in domain of SMRTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(N-(2-aminophenyl)-4-(1,3-dioxo-1,3-bis(phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed