BDBM50215276 CHEMBL399519::N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-(3,3,3-trifluoropropyl)ethanesulfonamide

SMILES CCS(=O)(=O)N(CCC(F)(F)F)c1c(Cl)c(Cl)cc2[nH]c(=O)c(=O)[nH]c12

InChI Key InChIKey=MVGABTCTHPSFLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215276   

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinox...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinox...)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215276(N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinox...)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at human NMDA NR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed