BDBM50215448 5-(3-chlorophenylethynyl)-5-methyl[1,2,4]triazine::CHEMBL390802

SMILES Cc1cnnc(n1)C#Cc1cccc(Cl)c1

InChI Key InChIKey=KPQLYWIRBOHKMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215448   

TargetMetabotropic glutamate receptor 5(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50215448(5-(3-chlorophenylethynyl)-5-methyl[1,2,4]triazine ...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHOK1 cells assessed as inhibition of glutamate-mediated internal calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed