BDBM50215456 3-(2-(3-fluorophenyl)ethynyl)-5-methyl-1,2,4-triazine::CHEMBL227201

SMILES Cc1cnnc(n1)C#Cc1cccc(F)c1

InChI Key InChIKey=QNQQWUGZWDWVGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215456   

TargetMetabotropic glutamate receptor 5(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50215456(3-(2-(3-fluorophenyl)ethynyl)-5-methyl-1,2,4-triaz...)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHOK1 cells assessed as inhibition of glutamate-mediated internal calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed