BDBM50215799 2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl)methylamino)-N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)benzamide::CHEMBL247792

SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccnc(NCCc4cnc[nH]4)c3)cc2O1

InChI Key InChIKey=FLYZOVOQWUDRBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215799   

TargetMast/stem cell growth factor receptor Kit(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215799(2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215799(2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...)
Affinity DataIC50: 146nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed