BDBM502158 N-[4-(1- methyl- [1,2,4]tria zolo[4,3- a]quinoxali ne-4- ylamino)- butyl]- benzamide::US11028090, Example 11

SMILES Cc1nnc2c(NCCCCNC(=O)c3ccccc3)nc3ccccc3n12

InChI Key InChIKey=WPISLGBRKJFEFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 502158   

LigandPNGBDBM502158(N-[4-(1- methyl- [1,2,4]tria zolo[4,3- a]quinoxali...)
Affinity DataKd:  29nMAssay Description:Binding affinity to human BRD4 BD1 expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by bromodomain analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM502158(N-[4-(1- methyl- [1,2,4]tria zolo[4,3- a]quinoxali...)
Affinity DataIC50: 58nMAssay Description:The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM502158(N-[4-(1- methyl- [1,2,4]tria zolo[4,3- a]quinoxali...)
Affinity DataKd:  180nMAssay Description:Binding affinity to human BRD4 BD2 expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by bromodomain analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed