BDBM50215828 CHEMBL233758::N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)-3-(3-(piperidin-1-yl)propyl)-3H-benzo[d]imidazole-5-carboxamide

SMILES CNC(=O)c1ccc(Nc2nc3ccc(cc3n2CCCN2CCCCC2)C(=O)N(CCC(C)C)CCC(C)C)cc1

InChI Key InChIKey=DADQHECQKQBHAW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50215828   

TargetMelanocortin receptor 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50215828(N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]NDP-alphaMSH from human melanocortin 4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50215828(N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]NDP-alphaMSH from human melanocortin 4 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50215828(N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]NDP-alphaMSH from human melanocortin 3 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50215828(N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)...)
Affinity DataKi:  880nMAssay Description:Displacement of [125I]NDP-alphaMSH from human melanocortin 5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50215828(N,N-diisopentyl-2-(4-(methylcarbamoyl)phenylamino)...)
Affinity DataKi:  9.30E+3nMAssay Description:Displacement of [125I]NDP-alphaMSH from human melanocortin 1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed