BDBM50215946 CHEMBL300129
SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(Cc2ccccc2)c2ccc(cc12)C(=O)Nc1c(Cl)cncc1Cl
InChI Key InChIKey=KCTNSZPDXIBCSV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50215946
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.75E+3nMAssay Description:Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Phosphodiesterase type IV (PDE4) obtained from guinea-pig macrophage was evaluatedMore data for this Ligand-Target Pair