BDBM50216393 CHEMBL231242::N-(2-(4-(2-fluorophenyl)piperazin-1-yl)-2-oxoethyl)quinoline-5-sulfonamide::quinolinesulfon-5-yl-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}amide

SMILES Fc1ccccc1N1CCN(CC1)C(=O)CNS(=O)(=O)c1cccc2ncccc12

InChI Key InChIKey=VVGDALNRAPAUGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216393   

TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50216393(N-(2-(4-(2-fluorophenyl)piperazin-1-yl)-2-oxoethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50216393(N-(2-(4-(2-fluorophenyl)piperazin-1-yl)-2-oxoethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed