BDBM50217577 CHEMBL236010::N-methyl(2-(4-(methylthio)phenoxy)-5-(4-thiomorpholinobutyl)phenyl)methanamine

SMILES CNCc1cc(CCCCN2CCSCC2)ccc1Oc1ccc(SC)cc1

InChI Key InChIKey=JVYJGMIWWGWCJQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217577   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217577(CHEMBL236010 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217577(CHEMBL236010 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217577(CHEMBL236010 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  9.70nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed