BDBM50217602 (Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid::CHEMBL231526

SMILES COc1cc(OC)cc(c1)-c1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1

InChI Key InChIKey=ZIZSHSPAAJIYOD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50217602   

TargetFibroblast growth factor receptor 1(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human FGFR1 kinase expressed in insect cell by HTRF detection methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human FGFR1 expressed in insect cells by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 780nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 930nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of rhFGF2-induced cellular proliferation of HUVECMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50217602((Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed