BDBM50217893 1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL398809

SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12

InChI Key InChIKey=ZCQPOBYGONRNAP-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217893   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217893(1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...)
Affinity DataKi:  1.29nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217893(1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217893(1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed