BDBM50217901 1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-sulfonyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL392976

SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1

InChI Key InChIKey=DAXDQRIJYKHPKB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217901   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217901(1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217901(1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-...)
Affinity DataKi:  3.24nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217901(1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed