BDBM50217909 3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(1-methyl-pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL392318

SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl

InChI Key InChIKey=XZRFRVDFACBFSQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217909   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217909(3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217909(3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed