BDBM50217929 3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidin-3-yl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL236571

SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1

InChI Key InChIKey=OAINFPLVHRTSJH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217929   

Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217929(3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...)
Affinity DataKi:  9.33nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217929(3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50217929(3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...)
Affinity DataIC50: 492nMAssay Description:Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed