BDBM50217931 8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-sulfonyl)-quinoline::CHEMBL400608

SMILES O=S(=O)(c1cn(C2CCNC2)c2ncccc12)c1cccc2cccnc12

InChI Key InChIKey=SRQPELDDXIRLNJ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217931   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217931(8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-s...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217931(8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-s...)
Affinity DataKi:  5.75nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217931(8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-s...)
Affinity DataIC50: 643nMAssay Description:Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed