BDBM50218291 CHEMBL394129::N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidin-3-yl)-5-chlorothiophene-2-carboxamide

SMILES CC(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key InChIKey=UBBAAVPYXDEHOX-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50218291   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  5.44E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(N-((3R,4S)-1-acetyl-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed