BDBM50218849 4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-[1,7]naphthyridine-3-carbonitrile::CHEMBL236384

SMILES N#Cc1cnc2cnc(NCc3cccnc3)cc2c1NC1CCCCCC1

InChI Key InChIKey=NMCXSWNTABUZSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218849   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218849(4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218849(4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed