BDBM50219054 2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]phenyl}-propanamide::CHEMBL389128

SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1

InChI Key InChIKey=BNQLJQAWDJNCDL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219054   

TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219054(2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]p...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]T-226296 from rat recombinant MCH1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219054(2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]p...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219054(2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]p...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed