BDBM50219058 CHEMBL244004::N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-acetamide

SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1

InChI Key InChIKey=ZGGXNCTZASWEAU-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219058   

TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219058(N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-pipe...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]T-226296 from rat recombinant MCH1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219058(N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-pipe...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219058(N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-pipe...)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed