BDBM50219383 3-[2-(4-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4-morpholin-4-yl-cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine::CHEMBL251534

SMILES Cc1ccc(Cc2nc3ccc(cc3[nH]2)-c2nn([C@H]3CC[C@@H](CC3)N3CCOCC3)c3ncnc(N)c23)cc1

InChI Key InChIKey=ZAVYATZDVJVQPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219383   

TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219383(3-[2-(4-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human IGF1R expressed in Sf21 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219383(3-[2-(4-methyl-benzyl)-1H-benzoimidazol-5-yl]-1-(4...)
Affinity DataIC50: 257nMAssay Description:Inhibition IGF1R phosphorylation in human MiaPaCa2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed