BDBM50219425 CHEMBL242533::N-hydroxy-3-[3-(1H-indole-2-carbonyl)phenyl]acrylamide

SMILES ONC(=O)\C=C\c1cccc(c1)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=YONXIFHNDNWCKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219425   

TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50219425(N-hydroxy-3-[3-(1H-indole-2-carbonyl)phenyl]acryla...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant HDAC1 in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50219425(N-hydroxy-3-[3-(1H-indole-2-carbonyl)phenyl]acryla...)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50219425(N-hydroxy-3-[3-(1H-indole-2-carbonyl)phenyl]acryla...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed