BDBM50219481 2-hydroxybiphenyl-3-carboxylic acid::CHEMBL229466

SMILES OC(=O)c1cccc(-c2ccccc2)c1O

InChI Key InChIKey=ZJWUEJOPKFYFQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219481   

TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219481BDBM50219481(2-hydroxybiphenyl-3-carboxylic acid | CHEMBL229466)
Affinity DataIC50: 2.40E+4nMAssay Description:Inverse agonist at human Gal4-HNFalpha-LBD expressed in HEK293T cells transfected with pFR-Luc/pRLSV40 assessed as relative luminescence measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219481BDBM50219481(2-hydroxybiphenyl-3-carboxylic acid | CHEMBL229466)
Affinity DataIC50: 8.59E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed